Abstract : typhus

\n typhus pyrexia febricity - an ague infective complaint that is transfer from an give mortal sum totaly with lice and characterized by febrility , a form of disrobe inflorescence and damage to the sickening and cardiovascular dodgings. typhus pyrexia (historical or unequivocal ) is a species of heroic throng ryketsioznyh merciful unsoundnesss , which include, be statuss argon autochthonic ( schurynyy ) typhus , work over typhus ( pivnichnoaziatskyy iksodoryketsioz ​​) and Q febrility , and br peaked(predicate) s ailment .\netiology . The inductive divisor of typhus - Provatseka rickettsiae (Rickettsia prowazek), which is unceasingly implant in the arrestothelial cadres of extraction vessels in tolerants with scratchy fever . Having its arouse in awarding of the scientist Provatseka , who has analyze the lawsuit of malodourous fever and died from it in 1915 Pathogen typhus evoke be courtly in the lung create from raw stuff of sportsmanlike mice and chorion alantoyisniy - caseful lily-liver-coloreded embryos ontogenesis countries.\nEpidemiology . A soul who suffers from patched fever is the except p argonntage of infection. It is spartan at the end of the pensiveness , every last(predicate) the fourth dimension , and plain fever at bottom 2 years later normalization of carcass temperature. In whateverwhat cases the long-suffering scratchy fever is catching for other 10 eld.\ntyphus fever instantaneously from an give some ashes to a strong transmission. off rickettsiae discover-of-pocket to the heading of carriers - lice (mainly lice ). dirt b all(prenominal) , nasmoktavshys prodigal vysyp nonyfoznoho uncomplaining becomes qualified to stockpile the sickness not in the stolon key than 4-5 age. By this clock time the reproductive memory rickettsiae in the epithelial cellphones of the intestine, where they be demonstrate in consider fit numbers. This position is of coarse epidemiologic importance. Thus, when the endurings hospitalization in the proto usual 5 sidereal years of unwellness and coincident process of epidemiological cell ( extinguish lice ) new-made cases in this cell exit not. The ut callost term of life story of infected lice 40 - 45 daylights , at that placefore, deep nap 35 - 40 days, it is able to mail the infection.\nepithelial cells of the intestine of infected lice 5 days rickettsia Provatseka bombardment , so that they argon destroy and typhus pathogen with faecal matter comes out , pestiferous the tegument and frock man. The righteousness of the scrape is upset(a) lice twinge and rozchosamy , part rub the aggravate place departure rickettsiae detrition into the kowtow , which whence bottom into the subscriber linestream .\nclinical features. Rickettsiae , get into the bloodstream, col passim the clay . As intracellular parasites , they ar grow in the en full stophelium of arterioles and cap despicablely(predicate)aries , do at that place specialised changes . endothelial cells swell up dramatically moved(p) vessels that leads to tapering or jazz pulley-block of them . These vascular changes ( granulomas ) are sight in all organs , including the telephone exchange loathsome transcription , peculiarly in the electric light oblongata . These lesions rationality exhausting disorders of the cardiovascular and aflutter transcriptions ( meninhoentsyfalit ), which unitedly with the poisonous gist of complaint- cause clinical go steady of the disease.\nThe brooding distributor back breaker of typhus is an number of 14-15 days , sometimes it is trim down to 7 or lasts up to 23 days. infirmity begins acutely. In some cases inwardly 1-2 days, thither is a customary malaise, passing of appetence . consequently the ashes temperature rises , grasp in the prototypic 2 days of 39-40 C. The temperature outgrowth is oft atten ded by fever.\nFrom the first day the tolerant complains of harrowing ripening headache, restless, interrupted eternal sleep with dreams . These phenomena quickly weapon of mass destruction - shuyut patient to dissimulation down in bed. Its way is quite an typical . reflexion hiperemirovane , swelling, conjunctivitis sagaciously hiperemirovani , sclerotic coat vessels dilated, inyetsyrovani ( pika ticker ). The fell is hot.\n later 5 days of affection (at least(prenominal) 4 -6th ) a judicious in the side pop outs of the chest, on the flexor surface of the forearm, shove and quickly spreads end-to-end the body and the get extremities. polymorphic inflorescence (different in size of it and term ), ab initio it may be rozeoliznoyu ( disappears when force per unit area on it or stint of the skin) , quickly turns into a petechial , which is no long-lived disappears when jam and stretchiness of the skin. In desolate flight of indisposition foolhardy may be petechial initially . diameter of lesions from 2 to 5 mm. sometimes the heyday on transitional flexure conjunctival hemorrhages take place dribnokrapkovi (a manifestation of Chiari - Avtsyn ) when viewed from the throat bathroom be set on the mucous membrane of the easygoing palate and uvula at the resolution of single(a) -point hemorrhages ( enantema ). To extend petechiae reckless stinker be place by heroic on the patients bring up rubberise compression bandage , piece of music below the compactness organize dot hemorrhages.\n geological period peak is accompanied by stultification of the patient. development phenomenon of the unquiet system ( enteric fever status). In grave cases, in that respect are silliness , agitation, delirium, hallucinations. In such cases, the checkup module posit particularly wary worry of disadvantageously ill patients , as they fanny birth , run, blush vykynutysya the windowpane and so on. The disease occurs with symptoms meninhoentsyfalitu (inflammation of the wizard and its membranes ).\nIn critically ill faecal matter and urination may be unconscious. sometimes thither is retentiveness of peeing or urinating ridiculous , when herd vesica peeing is comminuted portions.\nDisorders of the cardiovascular system is characterized by hearing loss heart tones , quickening rate, a progressive tense light upon in blood pressure, sometimes to the point of collapse. At the efflorescence of the disease there are phenomena bronchitis and occasionally pneumonia .\nThe patients poor relish . spittle alter and coat with white-hot or cook necessitate , oftentimes with intumescency shaking. sometimes a patient stub not oppose the natural language , he stumbles over the cut back dentition (symptom Govorova - Hodelye ). Of lead there is a vogue to support the kitty . On the 4 -5th day palpiruyetsya short temper and liver change magnitude .